Stanford scientists regenerate knee cartilage by blocking 15-PGDH, reducing osteoarthritis risk

Researchers at Stanford University published a study in Science demonstrating that blocking the protein 15-PGDH, which increases with aging, regenerates knee cartilage and reduces osteoarthritis risk. The finding is preliminary and based on animal models, with human applicability unproven. It matters as a potential therapeutic target for a common degenerative joint disease.